ClinVar Miner

Submissions for variant NM_000179.2(MSH6):c.628-8C>T (rs767991179)

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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Invitae RCV000228163 SCV000283851 likely benign Hereditary nonpolyposis colorectal neoplasms 2019-12-31 criteria provided, single submitter clinical testing
GeneDx RCV000432870 SCV000522507 likely benign not specified 2015-12-24 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Color RCV001184776 SCV001350841 likely benign Hereditary cancer-predisposing syndrome 2019-06-26 criteria provided, single submitter clinical testing

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