ClinVar Miner

Submissions for variant NM_000179.2(MSH6):c.642C>T (p.Tyr214=) (rs1800937)

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Total submissions: 14
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
ARUP Laboratories, Molecular Genetics and Genomics,ARUP Laboratories RCV000035327 SCV000604266 benign not specified 2017-01-09 criteria provided, single submitter clinical testing
Ambry Genetics RCV000132355 SCV000187444 benign Hereditary cancer-predisposing syndrome 2014-11-18 criteria provided, single submitter clinical testing
Color RCV000132355 SCV000292091 benign Hereditary cancer-predisposing syndrome 2014-11-26 criteria provided, single submitter clinical testing
DNA and Cytogenetics Diagnostics Unit,Erasmus Medical Center RCV000605855 SCV000744288 benign Hereditary nonpolyposis colorectal cancer type 5 2015-09-21 criteria provided, single submitter clinical testing
Department of Pathology and Laboratory Medicine,Sinai Health System RCV000035327 SCV000592571 benign not specified 2012-11-07 criteria provided, single submitter clinical testing
Diagnostic Laboratory, Department of Genetics,University Medical Center Groningen RCV000605855 SCV000734211 benign Hereditary nonpolyposis colorectal cancer type 5 no assertion criteria provided clinical testing
EGL Genetic Diagnostics,Eurofins Clinical Diagnostics RCV000035327 SCV000110163 benign not specified 2013-02-22 criteria provided, single submitter clinical testing
Illumina Clinical Services Laboratory,Illumina RCV000030277 SCV000430954 likely benign Lynch syndrome 2016-06-14 criteria provided, single submitter clinical testing
Integrated Genetics/Laboratory Corporation of America RCV000030277 SCV000052944 benign Lynch syndrome 2011-08-18 criteria provided, single submitter clinical testing Converted during submission to Benign.
International Society for Gastrointestinal Hereditary Tumours (InSiGHT) RCV000030277 SCV000108237 no known pathogenicity Lynch syndrome 2013-09-05 reviewed by expert panel research MAF >1%
Laboratory for Molecular Medicine,Partners HealthCare Personalized Medicine RCV000035327 SCV000058975 benign not specified 2011-09-21 criteria provided, single submitter clinical testing
Mayo Clinic Genetic Testing Laboratories,Mayo Clinic RCV000035327 SCV000257304 benign not specified no assertion criteria provided clinical testing
PreventionGenetics RCV000035327 SCV000302882 benign not specified criteria provided, single submitter clinical testing
True Health Diagnostics RCV000132355 SCV000788057 benign Hereditary cancer-predisposing syndrome 2018-02-27 no assertion criteria provided clinical testing

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