ClinVar Miner

Submissions for variant NM_000179.3(MSH6):c.136_158del (p.Gly46fs)

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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Myriad Genetics, Inc. RCV003450282 SCV004185857 pathogenic Lynch syndrome 5 2023-08-09 criteria provided, single submitter clinical testing This variant is considered pathogenic. This variant creates a frameshift predicted to result in premature protein truncation.
Baylor Genetics RCV003459868 SCV004198165 likely pathogenic Endometrial carcinoma 2022-03-31 criteria provided, single submitter clinical testing

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