ClinVar Miner

Submissions for variant NM_000179.3(MSH6):c.1461G>A (p.Glu487=)

gnomAD frequency: 0.00001  dbSNP: rs1174736855
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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Color Diagnostics, LLC DBA Color Health RCV001524091 SCV001733860 likely benign Hereditary cancer-predisposing syndrome 2020-06-22 criteria provided, single submitter clinical testing
Invitae RCV002070300 SCV002360657 likely benign Hereditary nonpolyposis colorectal neoplasms 2023-09-12 criteria provided, single submitter clinical testing
All of Us Research Program, National Institutes of Health RCV004007254 SCV004843644 likely benign Lynch syndrome 2023-12-13 criteria provided, single submitter clinical testing

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