ClinVar Miner

Submissions for variant NM_000179.3(MSH6):c.4001+4_4001+8dup (rs587782853)

Minimum review status: Collection method:
Minimum conflict level:
ClinVar version:
Total submissions: 8
Download table as spreadsheet
Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000132454 SCV000187548 likely benign Hereditary cancer-predisposing syndrome 2019-10-01 criteria provided, single submitter clinical testing RNA Studies;In silico models in agreement (benign)
GeneDx RCV000132454 SCV000211367 benign Hereditary cancer-predisposing syndrome 2014-09-17 criteria provided, single submitter clinical testing The variant is found in BR-OV-HEREDIC panel(s).
Invitae RCV001080987 SCV000253115 likely benign Hereditary nonpolyposis colorectal neoplasms 2019-12-16 criteria provided, single submitter clinical testing
Counsyl RCV000409890 SCV000489495 likely benign Hereditary nonpolyposis colorectal cancer type 5 2016-10-11 criteria provided, single submitter clinical testing
Department of Pathology and Laboratory Medicine,Sinai Health System RCV000503472 SCV000592667 uncertain significance not specified criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000196451 SCV000601599 likely benign not provided 2019-03-11 criteria provided, single submitter clinical testing
Color RCV000132454 SCV000902893 likely benign Hereditary cancer-predisposing syndrome 2016-12-13 criteria provided, single submitter clinical testing
Mendelics RCV000409890 SCV001135860 likely benign Hereditary nonpolyposis colorectal cancer type 5 2019-05-28 criteria provided, single submitter clinical testing

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.