Submissions for variant NM_000233.4(LHCGR):c.50_55dup (p.Leu17_Gln18dup) (rs71245621)

Total submissions: 6

Submitter	RCV	SCV	Clinical significance	Condition	Last evaluated	Review status	Method	Comment
EGL Genetic Diagnostics, Eurofins Clinical Diagnostics	RCV000303287	SCV000331441	benign	not specified	2016-08-23	criteria provided, single submitter	clinical testing
Illumina Clinical Services Laboratory,Illumina	RCV000378063	SCV000431077	benign	Gonadotropin-independent familial sexual precocity	2016-06-14	criteria provided, single submitter	clinical testing
Illumina Clinical Services Laboratory,Illumina	RCV000283585	SCV000431078	benign	Hypergonadotropic hypogonadism	2016-06-14	criteria provided, single submitter	clinical testing
Illumina Clinical Services Laboratory,Illumina	RCV000319880	SCV000431079	benign	Leydig cell hypoplasia, type 1	2016-06-14	criteria provided, single submitter	clinical testing
Athena Diagnostics Inc	RCV000303287	SCV000614018	benign	not specified	2017-07-26	criteria provided, single submitter	clinical testing
GeneDx	RCV000303287	SCV000728653	benign	not specified	2017-07-24	criteria provided, single submitter	clinical testing	This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.