ClinVar Miner

Submissions for variant NM_000245.4(MET):c.1650A>G (p.Glu550=)

dbSNP: rs2116836870
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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Labcorp Genetics (formerly Invitae), Labcorp RCV001482185 SCV001686546 likely benign Renal cell carcinoma 2020-06-16 criteria provided, single submitter clinical testing
Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital RCV003493859 SCV004243308 likely benign not specified 2025-03-04 criteria provided, single submitter clinical testing
Myriad Genetics, Inc. RCV005247183 SCV005898376 benign Papillary renal cell carcinoma type 1 2024-11-07 criteria provided, single submitter clinical testing This variant is considered benign. This variant is a silent/synonymous amino acid change and it is not expected to impact splicing.

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