Total submissions: 3
Submitter | RCV | SCV | Clinical significance | Condition | Last evaluated | Review status | Method | Comment |
---|---|---|---|---|---|---|---|---|
Labcorp Genetics |
RCV001457731 | SCV001661536 | likely benign | Renal cell carcinoma | 2023-08-06 | criteria provided, single submitter | clinical testing | |
Ambry Genetics | RCV002320035 | SCV002610088 | likely benign | Hereditary cancer-predisposing syndrome | 2020-06-11 | criteria provided, single submitter | clinical testing | This alteration is classified as likely benign based on a combination of the following: seen in unaffected individuals, population frequency, intact protein function, lack of segregation with disease, co-occurrence, RNA analysis, in silico models, amino acid conservation, lack of disease association in case-control studies, and/or the mechanism of disease or impacted region is inconsistent with a known cause of pathogenicity. |
Ce |
RCV003432837 | SCV004158930 | likely benign | not provided | 2024-06-01 | criteria provided, single submitter | clinical testing | MET: BP4, BP7 |