ClinVar Miner

Submissions for variant NM_000249.3(MLH1):c.1043T>C (p.Leu348Ser) (rs755401753)

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Total submissions: 1
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000218677 SCV000274753 likely benign Hereditary cancer-predisposing syndrome 2015-03-23 criteria provided, single submitter clinical testing Lines of evidence used in support of classification: In silico models in agreement (benign),Other data supporting benign classification

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