Total submissions: 5
Submitter | RCV | SCV | Clinical significance | Condition | Last evaluated | Review status | Method | Comment |
---|---|---|---|---|---|---|---|---|
International Society for Gastrointestinal Hereditary Tumours |
RCV000075643 | SCV000106649 | no known pathogenicity | Lynch syndrome | 2013-09-05 | reviewed by expert panel | research | Multifactorial likelihood analysis posterior probability <0.001 |
Institute for Biomarker Research, |
RCV000209433 | SCV000679730 | likely benign | Hereditary cancer-predisposing syndrome | 2017-07-12 | criteria provided, single submitter | clinical testing | |
Gene |
RCV000829443 | SCV000971173 | likely benign | not provided | 2018-06-17 | criteria provided, single submitter | clinical testing | This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease. |
Mayo Clinic Genetic Testing Laboratories, |
RCV000202118 | SCV000257096 | likely benign | not specified | no assertion criteria provided | clinical testing | ||
University of Washington Department of Laboratory Medicine, |
RCV000209433 | SCV000265270 | likely benign | Hereditary cancer-predisposing syndrome | 2015-12-01 | no assertion criteria provided | clinical testing |