ClinVar Miner

Submissions for variant NM_000249.3(MLH1):c.380+16C>G (rs121909452)

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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV000422300 SCV000532951 likely benign not specified 2016-10-13 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Narod's Lab, University of Toronto RCV000059815 SCV000091385 not provided not provided no assertion provided not provided

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