Total submissions: 4
Submitter | RCV | SCV | Clinical significance | Condition | Last evaluated | Review status | Method | Comment |
---|---|---|---|---|---|---|---|---|
International Society for Gastrointestinal Hereditary Tumours |
RCV000030225 | SCV000106717 | no known pathogenicity | Lynch syndrome | 2013-09-05 | reviewed by expert panel | research | Multifactorial likelihood analysis posterior probability <0.001 |
Integrated Genetics/Laboratory Corporation of America | RCV000030225 | SCV000052892 | benign | Lynch syndrome | 2011-08-18 | criteria provided, single submitter | curation | Converted during submission to Benign. |
Gene |
RCV000829444 | SCV000971174 | likely benign | not provided | 2018-06-17 | criteria provided, single submitter | clinical testing | This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease. |
Mayo Clinic Genetic Testing Laboratories, |
RCV000202105 | SCV000257099 | likely benign | not specified | no assertion criteria provided | clinical testing |