ClinVar Miner

Submissions for variant NM_000249.3(MLH1):c.588+11G>C (rs4647258)

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Total submissions: 8
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Color RCV000580337 SCV000684845 benign Hereditary cancer-predisposing syndrome 2015-04-13 criteria provided, single submitter clinical testing
EGL Genetic Diagnostics,Eurofins Clinical Diagnostics RCV000078419 SCV000110267 benign not specified 2013-06-06 criteria provided, single submitter clinical testing
Illumina Clinical Services Laboratory,Illumina RCV000030228 SCV000443328 likely benign Lynch syndrome 2016-06-14 criteria provided, single submitter clinical testing
Integrated Genetics/Laboratory Corporation of America RCV000030228 SCV000052895 benign Lynch syndrome 2010-09-28 no assertion criteria provided clinical testing
International Society for Gastrointestinal Hereditary Tumours (InSiGHT) RCV000490567 SCV000106777 benign Lynch syndrome I 2014-10-10 reviewed by expert panel research MAF >1%
Mayo Clinic Genetic Testing Laboratories,Mayo Clinic RCV000078419 SCV000257106 benign not specified no assertion criteria provided clinical testing
Narod's Lab, University of Toronto RCV000059818 SCV000091388 not provided not provided no assertion provided not provided
PreventionGenetics RCV000078419 SCV000805975 benign not specified 2016-11-03 criteria provided, single submitter clinical testing

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