ClinVar Miner

Submissions for variant NM_000249.3(MLH1):c.589-15C>T (rs55658850)

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Total submissions: 5
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Color RCV000580940 SCV000684846 benign Hereditary cancer-predisposing syndrome 2015-04-13 criteria provided, single submitter clinical testing
Integrated Genetics/Laboratory Corporation of America RCV000030229 SCV000052896 benign Lynch syndrome 2011-04-22 no assertion criteria provided clinical testing
International Society for Gastrointestinal Hereditary Tumours (InSiGHT) RCV000030229 SCV000106788 likely benign Lynch syndrome 2013-09-05 reviewed by expert panel research MAF >1% in African population
Mayo Clinic Genetic Testing Laboratories,Mayo Clinic RCV000202179 SCV000257108 benign not specified no assertion criteria provided research
PreventionGenetics RCV000202179 SCV000303151 benign not specified criteria provided, single submitter clinical testing

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