ClinVar Miner

Submissions for variant NM_000249.3(MLH1):c.791-14T>C (rs751254837)

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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Color RCV000580579 SCV000684868 likely benign Hereditary cancer-predisposing syndrome 2017-03-20 criteria provided, single submitter clinical testing
Counsyl RCV000409272 SCV000488919 likely benign Lynch syndrome II 2016-07-18 criteria provided, single submitter clinical testing
GeneDx RCV000423401 SCV000513616 likely benign not specified 2017-01-10 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.

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