ClinVar Miner

Submissions for variant NM_000249.3(MLH1):c.885-24T>A (rs201594027)

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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
International Society for Gastrointestinal Hereditary Tumours (InSiGHT) RCV000075913 SCV000106933 likely benign Lynch syndrome 2013-09-05 reviewed by expert panel research Intronic substitution with no effect on splicing & MAF 0.01-1%
Mayo Clinic Genetic Testing Laboratories,Mayo Clinic RCV000202112 SCV000257119 likely benign not specified no assertion criteria provided clinical testing
University of Washington Department of Laboratory Medicine, University of Washington RCV000209228 SCV000265258 likely benign Hereditary cancer-predisposing syndrome 2015-12-01 no assertion criteria provided clinical testing

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