ClinVar Miner

Submissions for variant NM_000249.4(MLH1):c.1392T>C (p.Pro464=) (rs63750201)

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Total submissions: 6
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000162675 SCV000213122 likely benign Hereditary cancer-predisposing syndrome 2014-09-18 criteria provided, single submitter clinical testing
Invitae RCV000524236 SCV000253133 likely benign Hereditary nonpolyposis colorectal neoplasms 2019-12-31 criteria provided, single submitter clinical testing
Color RCV000162675 SCV000689805 likely benign Hereditary cancer-predisposing syndrome 2016-02-24 criteria provided, single submitter clinical testing
Mendelics RCV000075186 SCV000838016 uncertain significance Lynch syndrome 2018-07-02 criteria provided, single submitter clinical testing
Mendelics RCV000987176 SCV001136412 uncertain significance Lynch syndrome II 2019-05-28 criteria provided, single submitter clinical testing
Integrated Genetics/Laboratory Corporation of America RCV001192574 SCV001360801 likely benign not specified 2020-01-31 criteria provided, single submitter clinical testing

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