ClinVar Miner

Submissions for variant NM_000249.4(MLH1):c.306+6C>T

dbSNP: rs746641892
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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Labcorp Genetics (formerly Invitae), Labcorp RCV001201379 SCV000284058 likely benign Hereditary nonpolyposis colorectal neoplasms 2024-11-11 criteria provided, single submitter clinical testing
Mendelics RCV000987148 SCV001136371 uncertain significance Colorectal cancer, hereditary nonpolyposis, type 2 2019-05-28 criteria provided, single submitter clinical testing
Myriad Genetics, Inc. RCV000987148 SCV005898807 likely benign Colorectal cancer, hereditary nonpolyposis, type 2 2024-11-18 criteria provided, single submitter clinical testing This variant is considered likely benign. This variant is intronic and is not expected to impact mRNA splicing.

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