Total submissions: 9
Submitter | RCV | SCV | Clinical significance | Condition | Last evaluated | Review status | Method | Comment |
---|---|---|---|---|---|---|---|---|
International Society for Gastrointestinal Hereditary Tumours |
RCV000030225 | SCV000106717 | no known pathogenicity | Lynch syndrome | 2013-09-05 | reviewed by expert panel | research | Multifactorial likelihood analysis posterior probability <0.001 |
Women's Health and Genetics/Laboratory Corporation of America, |
RCV000030225 | SCV000052892 | benign | Lynch syndrome | 2011-08-18 | criteria provided, single submitter | curation | Converted during submission to Benign. |
Gene |
RCV000829444 | SCV000971174 | likely benign | not provided | 2018-06-17 | criteria provided, single submitter | clinical testing | This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease. |
Center for Genomic Medicine, |
RCV000202105 | SCV002552428 | benign | not specified | 2023-08-15 | criteria provided, single submitter | clinical testing | |
KCCC/NGS Laboratory, |
RCV003315513 | SCV004015864 | benign | Colorectal cancer, hereditary nonpolyposis, type 2 | 2023-07-07 | criteria provided, single submitter | clinical testing | |
Mayo Clinic Laboratories, |
RCV000202105 | SCV000257099 | likely benign | not specified | no assertion criteria provided | clinical testing | ||
Joint Genome Diagnostic Labs from Nijmegen and Maastricht, |
RCV000202105 | SCV001957106 | benign | not specified | no assertion criteria provided | clinical testing | ||
Clinical Genetics DNA and cytogenetics Diagnostics Lab, |
RCV000202105 | SCV001964161 | benign | not specified | no assertion criteria provided | clinical testing | ||
Clinical Genetics Laboratory, |
RCV000202105 | SCV001977618 | benign | not specified | no assertion criteria provided | clinical testing |