ClinVar Miner

Submissions for variant NM_000251.2(MSH2):c.1662-9G>A (rs17218356)

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Total submissions: 9
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Center for Human Genetics, Inc RCV000625493 SCV000781772 uncertain significance Lynch syndrome I 2016-11-01 criteria provided, single submitter clinical testing
Color RCV000579780 SCV000684961 benign Hereditary cancer-predisposing syndrome 2015-02-18 criteria provided, single submitter clinical testing
Department of Pathology and Laboratory Medicine,Sinai Health System RCV000202150 SCV000592514 likely benign not specified 2016-10-14 criteria provided, single submitter clinical testing
Genome Diagnostics Laboratory,VU University Medical Center Amsterdam RCV000625493 SCV000745640 benign Lynch syndrome I 2017-09-07 no assertion criteria provided clinical testing
Illumina Clinical Services Laboratory,Illumina RCV000076227 SCV000430927 likely benign Lynch syndrome 2016-06-14 criteria provided, single submitter clinical testing
International Society for Gastrointestinal Hereditary Tumours (InSiGHT) RCV000076227 SCV000107250 no known pathogenicity Lynch syndrome 2013-09-05 reviewed by expert panel research Multifactorial likelihood analysis posterior probability <0.001
Invitae RCV000524351 SCV000262285 benign Hereditary nonpolyposis colon cancer 2018-01-13 criteria provided, single submitter clinical testing
Mayo Clinic Genetic Testing Laboratories,Mayo Clinic RCV000202150 SCV000257148 uncertain significance not specified no assertion criteria provided research
PreventionGenetics RCV000202150 SCV000806007 benign not specified 2017-01-17 criteria provided, single submitter clinical testing

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