ClinVar Miner

Submissions for variant NM_000251.2(MSH2):c.2580G>T (p.Ser860=) (rs752428475)

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Total submissions: 6
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Invitae RCV000560582 SCV000625393 likely benign not provided 2018-10-04 criteria provided, single submitter clinical testing
Women's Health and Genetics/Laboratory Corporation of America, LabCorp RCV000589941 SCV000696252 likely benign not specified 2019-08-29 criteria provided, single submitter clinical testing
Ambry Genetics RCV001016007 SCV001176910 likely benign Hereditary cancer-predisposing syndrome 2019-09-30 criteria provided, single submitter clinical testing In silico models in agreement (benign);Synonymous alterations with insufficient evidence to classify as benign
Invitae RCV001443052 SCV001646012 likely benign Hereditary nonpolyposis colorectal neoplasms 2020-09-03 criteria provided, single submitter clinical testing
GeneDx RCV000560582 SCV001764140 likely benign not provided 2019-04-16 criteria provided, single submitter clinical testing
Department of Pathology and Laboratory Medicine,Sinai Health System RCV000560582 SCV001551513 uncertain significance not provided no assertion criteria provided clinical testing

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