ClinVar Miner

Submissions for variant NM_000251.3(MSH2):c.1746C>G (p.Val582=)

dbSNP: rs786201486
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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Labcorp Genetics (formerly Invitae), Labcorp RCV001450901 SCV001654520 likely benign Hereditary nonpolyposis colorectal neoplasms 2023-05-17 criteria provided, single submitter clinical testing
Myriad Genetics, Inc. RCV005246067 SCV005895763 benign Lynch syndrome 1 2024-12-10 criteria provided, single submitter clinical testing This variant is considered benign. This variant is a silent/synonymous amino acid change and it is not expected to impact splicing.

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