ClinVar Miner

Submissions for variant NM_000251.3(MSH2):c.211+98T>C

gnomAD frequency: 0.55408  dbSNP: rs3815865
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Total submissions: 4
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
International Society for Gastrointestinal Hereditary Tumours (InSiGHT) RCV000076393 SCV000107419 no known pathogenicity Lynch syndrome 2013-09-05 reviewed by expert panel research MAF >1%
GeneDx RCV001636635 SCV001848810 benign not provided 2015-03-03 criteria provided, single submitter clinical testing
Labcorp Genetics (formerly Invitae), Labcorp RCV002055086 SCV002405396 benign Hereditary nonpolyposis colorectal neoplasms 2025-02-04 criteria provided, single submitter clinical testing
Breakthrough Genomics, Breakthrough Genomics RCV001636635 SCV005241320 benign not provided criteria provided, single submitter not provided

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