ClinVar Miner

Submissions for variant NM_000251.3(MSH2):c.2121C>T (p.Cys707=)

dbSNP: rs1553369139
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Total submissions: 4
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Color Diagnostics, LLC DBA Color Health RCV000581264 SCV000690049 likely benign Hereditary cancer-predisposing syndrome 2017-04-24 criteria provided, single submitter clinical testing
Invitae RCV002065091 SCV002494016 likely benign Hereditary nonpolyposis colorectal neoplasms 2024-01-12 criteria provided, single submitter clinical testing
Sema4, Sema4 RCV000581264 SCV002534449 likely benign Hereditary cancer-predisposing syndrome 2021-02-09 criteria provided, single submitter curation
All of Us Research Program, National Institutes of Health RCV004002333 SCV004827851 likely benign Lynch syndrome 2023-08-15 criteria provided, single submitter clinical testing

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