ClinVar Miner

Submissions for variant NM_000251.3(MSH2):c.2458+9T>C

gnomAD frequency: 0.00001  dbSNP: rs864622575
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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Labcorp Genetics (formerly Invitae), Labcorp RCV000206349 SCV000261173 likely benign Hereditary nonpolyposis colorectal neoplasms 2024-10-02 criteria provided, single submitter clinical testing
Myriad Genetics, Inc. RCV005246800 SCV005897472 likely benign Lynch syndrome 1 2024-12-13 criteria provided, single submitter clinical testing This variant is considered likely benign. This variant is intronic and is not expected to impact mRNA splicing.

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