Submissions for variant NM_000251.3(MSH2):c.942+25_942+29del

dbSNP: rs11309117

Total submissions: 11

Submitter	RCV	SCV	Clinical significance	Condition	Last evaluated	Review status	Method	Comment
Genomic Diagnostic Laboratory, Division of Genomic Diagnostics, Children's Hospital of Philadelphia	RCV000239020	SCV000296896	benign	Lynch syndrome	2015-11-11	criteria provided, single submitter	clinical testing
Mendelics	RCV000986658	SCV001135714	likely benign	Lynch syndrome 1	2019-05-28	criteria provided, single submitter	clinical testing
Institute of Human Genetics, University of Leipzig Medical Center	RCV000986658	SCV001429073	uncertain significance	Lynch syndrome 1	2018-07-09	criteria provided, single submitter	clinical testing
Invitae	RCV001514763	SCV001722682	benign	Hereditary nonpolyposis colorectal neoplasms	2022-11-14	criteria provided, single submitter	clinical testing
GeneDx	RCV000860492	SCV001770490	likely benign	not provided	2020-08-19	criteria provided, single submitter	clinical testing
Sema4, Sema4	RCV002255344	SCV002526763	benign	Hereditary cancer-predisposing syndrome	2021-09-16	criteria provided, single submitter	curation
Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital	RCV001529140	SCV002552209	benign	not specified	2023-08-15	criteria provided, single submitter	clinical testing
Institute for Biomarker Research, Medical Diagnostic Laboratories, L.L.C.	RCV002255344	SCV002819200	benign	Hereditary cancer-predisposing syndrome	2022-05-11	criteria provided, single submitter	clinical testing
Diagnostic Laboratory, Department of Genetics, University Medical Center Groningen	RCV001529140	SCV001742110	benign	not specified		no assertion criteria provided	clinical testing
Laboratory of Diagnostic Genome Analysis, Leiden University Medical Center (LUMC)	RCV001529140	SCV001798296	benign	not specified		no assertion criteria provided	clinical testing
Clinical Genetics, Academic Medical Center	RCV001529140	SCV001923593	benign	not specified		no assertion criteria provided	clinical testing