ClinVar Miner

Submissions for variant NM_000256.3(MYBPC3):c.851+18C>T

gnomAD frequency: 0.00009  dbSNP: rs377287239
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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV000421228 SCV000513750 likely benign not specified 2017-11-15 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Invitae RCV002521527 SCV003298374 likely benign Hypertrophic cardiomyopathy 2024-01-31 criteria provided, single submitter clinical testing
ARUP Laboratories, Molecular Genetics and Genomics, ARUP Laboratories RCV003736758 SCV004563353 likely benign not provided 2023-11-03 criteria provided, single submitter clinical testing

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