ClinVar Miner

Submissions for variant NM_000257.4(MYH7):c.4353+10G>A (rs202205780)

Minimum review status: Collection method:
Minimum conflict level:
ClinVar version:
Total submissions: 5
Download table as spreadsheet
Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Athena Diagnostics Inc RCV000712358 SCV000842832 likely benign not provided 2018-01-26 criteria provided, single submitter clinical testing
EGL Genetic Diagnostics,Eurofins Clinical Diagnostics RCV000035904 SCV000229297 benign not specified 2015-01-23 criteria provided, single submitter clinical testing
Invitae RCV000200271 SCV000252662 benign Hypertrophic cardiomyopathy 2017-12-29 criteria provided, single submitter clinical testing
Laboratory for Molecular Medicine,Partners HealthCare Personalized Medicine RCV000035904 SCV000059555 benign not specified 2012-03-02 criteria provided, single submitter clinical testing 4353+10G>A in intron 31 of MYH7: This variant is not expected to have clinical s ignificance because it has been identified in 0.7% (27/3738) of African American chromosomes from a broad population by the NHLBI Exome Sequencing Project (http ://evs.gs.washington.edu/EVS).
PreventionGenetics RCV000035904 SCV000303235 benign not specified criteria provided, single submitter clinical testing

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.