ClinVar Miner

Submissions for variant NM_000260.4(MYO7A):c.4323+35G>T

gnomAD frequency: 0.59156  dbSNP: rs1109977
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Total submissions: 6
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
PreventionGenetics, part of Exact Sciences RCV000244381 SCV000303295 benign not specified criteria provided, single submitter clinical testing
GeneDx RCV000829528 SCV000971258 benign not provided 2018-06-13 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Genome-Nilou Lab RCV001778825 SCV002015936 benign Autosomal dominant nonsyndromic hearing loss 11 2021-09-05 criteria provided, single submitter clinical testing
Genome-Nilou Lab RCV001778824 SCV002015937 benign Autosomal recessive nonsyndromic hearing loss 2 2021-09-05 criteria provided, single submitter clinical testing
Genome-Nilou Lab RCV001778826 SCV002015938 benign Usher syndrome type 1 2021-09-05 criteria provided, single submitter clinical testing
Breakthrough Genomics, Breakthrough Genomics RCV000829528 SCV005229918 benign not provided criteria provided, single submitter not provided

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