ClinVar Miner

Submissions for variant NM_000260.4(MYO7A):c.736-47C>A

gnomAD frequency: 0.11805  dbSNP: rs3737454
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Total submissions: 6
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
PreventionGenetics, part of Exact Sciences RCV000246986 SCV000303313 benign not specified criteria provided, single submitter clinical testing
GeneDx RCV000835222 SCV000977009 benign not provided 2018-06-14 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Genome-Nilou Lab RCV001533390 SCV001749276 benign Autosomal dominant nonsyndromic hearing loss 11 2021-07-01 criteria provided, single submitter clinical testing
Genome-Nilou Lab RCV001533391 SCV001749277 benign Autosomal recessive nonsyndromic hearing loss 2 2021-07-01 criteria provided, single submitter clinical testing
Genome-Nilou Lab RCV001533392 SCV001749278 benign Usher syndrome type 1 2021-07-01 criteria provided, single submitter clinical testing
Breakthrough Genomics, Breakthrough Genomics RCV000835222 SCV005236185 benign not provided criteria provided, single submitter not provided

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