ClinVar Miner

Submissions for variant NM_000335.5(SCN5A):c.1572C>A (p.Ser524=)

dbSNP: rs1553704216
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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV000600650 SCV000724458 likely benign not specified 2017-11-08 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
All of Us Research Program, National Institutes of Health RCV004002562 SCV004838508 likely benign Cardiac arrhythmia 2023-12-18 criteria provided, single submitter clinical testing

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