ClinVar Miner

Submissions for variant NM_000363.5(TNNI3):c.432G>T (p.Leu144=) (rs776615304)

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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV000441523 SCV000514921 likely benign not specified 2016-01-04 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Color Health, Inc RCV001184558 SCV001350567 likely benign Cardiomyopathy 2020-02-04 criteria provided, single submitter clinical testing
Invitae RCV001445635 SCV001648669 likely benign Hypertrophic cardiomyopathy 2019-04-11 criteria provided, single submitter clinical testing

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