ClinVar Miner

Submissions for variant NM_000363.5(TNNI3):c.471G>A (p.Ala157=) (rs747756509)

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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV000168951 SCV000527783 likely benign not specified 2016-05-12 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Invitae RCV000874802 SCV001017030 likely benign Hypertrophic cardiomyopathy 2020-05-10 criteria provided, single submitter clinical testing
Color Health, Inc RCV001180806 SCV001345827 likely benign Cardiomyopathy 2019-12-09 criteria provided, single submitter clinical testing

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