ClinVar Miner

Submissions for variant NM_000421.5(KRT10):c.75T>C (p.Cys25=)

dbSNP: rs1555549255
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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV001681342 SCV001899413 benign not provided 2015-03-03 criteria provided, single submitter clinical testing
PreventionGenetics, part of Exact Sciences RCV003941071 SCV004760015 likely benign KRT10-related disorder 2023-08-01 no assertion criteria provided clinical testing This variant is classified as likely benign based on ACMG/AMP sequence variant interpretation guidelines (Richards et al. 2015 PMID: 25741868, with internal and published modifications).

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