ClinVar Miner

Submissions for variant NM_000455.4(STK11):c.1050C>T (p.Asp350=) (rs779583262)

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Total submissions: 4
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000163620 SCV000214187 likely benign Hereditary cancer-predisposing syndrome 2014-12-08 criteria provided, single submitter clinical testing
Invitae RCV000541935 SCV000629057 likely benign Peutz-Jeghers syndrome 2017-11-12 criteria provided, single submitter clinical testing
Color RCV000163620 SCV000686582 likely benign Hereditary cancer-predisposing syndrome 2017-01-25 criteria provided, single submitter clinical testing
GeneDx RCV000614911 SCV000729258 likely benign not specified 2017-11-21 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.

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