ClinVar Miner

Submissions for variant NM_000455.4(STK11):c.396C>T (p.Cys132=) (rs730881969)

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Total submissions: 5
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000163260 SCV000213788 likely benign Hereditary cancer-predisposing syndrome 2015-05-24 criteria provided, single submitter clinical testing
Invitae RCV000204600 SCV000259742 likely benign not provided 2019-01-09 criteria provided, single submitter clinical testing
GeneDx RCV000434058 SCV000520552 likely benign not specified 2015-11-05 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Color RCV000163260 SCV000691499 likely benign Hereditary cancer-predisposing syndrome 2015-08-17 criteria provided, single submitter clinical testing
Integrated Genetics/Laboratory Corporation of America RCV000434058 SCV000918289 likely benign not specified 2019-08-29 criteria provided, single submitter clinical testing

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