ClinVar Miner

Submissions for variant NM_000455.4(STK11):c.597+8C>T (rs565387911)

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Total submissions: 5
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV000213014 SCV000171887 benign not specified 2014-04-01 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Ambry Genetics RCV000131656 SCV000186683 likely benign Hereditary cancer-predisposing syndrome 2013-05-22 criteria provided, single submitter clinical testing
Invitae RCV000457082 SCV000554150 likely benign Peutz-Jeghers syndrome 2017-12-20 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000213014 SCV000602231 likely benign not specified 2017-01-07 criteria provided, single submitter clinical testing
Color RCV000131656 SCV000686667 likely benign Hereditary cancer-predisposing syndrome 2016-01-06 criteria provided, single submitter clinical testing

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