ClinVar Miner

Submissions for variant NM_000455.4(STK11):c.598-8C>T (rs373610101)

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Total submissions: 8
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Invitae RCV000123063 SCV000166358 benign Peutz-Jeghers syndrome 2018-01-22 criteria provided, single submitter clinical testing
Ambry Genetics RCV000131148 SCV000186088 likely benign Hereditary cancer-predisposing syndrome 2015-01-22 criteria provided, single submitter clinical testing
GeneDx RCV000213015 SCV000211683 benign not specified 2014-08-15 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Institute for Biomarker Research,Medical Diagnostic Laboratories, L.L.C. RCV000131148 SCV000576426 likely benign Hereditary cancer-predisposing syndrome 2017-02-14 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000213015 SCV000602233 likely benign not specified 2017-04-13 criteria provided, single submitter clinical testing
Color RCV000131148 SCV000686669 benign Hereditary cancer-predisposing syndrome 2015-11-17 criteria provided, single submitter clinical testing
Integrated Genetics/Laboratory Corporation of America RCV000589505 SCV000696724 benign not provided 2016-01-25 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000589505 SCV000889862 benign not provided 2018-04-13 criteria provided, single submitter clinical testing

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