ClinVar Miner

Submissions for variant NM_000455.4(STK11):c.621C>T (p.Asp207=) (rs569380138)

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Total submissions: 6
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000163122 SCV000213634 likely benign Hereditary cancer-predisposing syndrome 2014-10-22 criteria provided, single submitter clinical testing
Invitae RCV000230661 SCV000284871 likely benign Peutz-Jeghers syndrome 2017-08-23 criteria provided, single submitter clinical testing
Counsyl RCV000230661 SCV000489440 likely benign Peutz-Jeghers syndrome 2016-10-05 criteria provided, single submitter clinical testing
Color RCV000163122 SCV000691531 likely benign Hereditary cancer-predisposing syndrome 2017-08-10 criteria provided, single submitter clinical testing
GeneDx RCV000606691 SCV000729206 likely benign not specified 2017-03-03 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000759356 SCV000888642 likely benign not provided 2017-08-30 criteria provided, single submitter clinical testing

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