ClinVar Miner

Submissions for variant NM_000455.4(STK11):c.734+20G>A (rs375315233)

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Total submissions: 5
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000128909 SCV000172776 likely benign Hereditary cancer-predisposing syndrome 2016-11-23 criteria provided, single submitter clinical testing Lines of evidence used in support of classification: Other data supporting benign classification
Color RCV000128909 SCV000686683 likely benign Hereditary cancer-predisposing syndrome 2015-05-28 criteria provided, single submitter clinical testing
Counsyl RCV000410646 SCV000489195 likely benign Peutz-Jeghers syndrome 2016-08-31 criteria provided, single submitter clinical testing
GeneDx RCV000213017 SCV000171888 benign not specified 2014-02-12 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Mayo Clinic Genetic Testing Laboratories,Mayo Clinic RCV000213017 SCV000692049 uncertain significance not specified no assertion criteria provided clinical testing

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