ClinVar Miner

Submissions for variant NM_000455.4(STK11):c.787T>C (p.Leu263=) (rs372378119)

Minimum review status: Collection method:
Minimum conflict level:
ClinVar version:
Total submissions: 7
Download table as spreadsheet
Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV000213018 SCV000171889 benign not specified 2014-04-24 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Ambry Genetics RCV000128297 SCV000213594 likely benign Hereditary cancer-predisposing syndrome 2014-07-12 criteria provided, single submitter clinical testing
Invitae RCV000200266 SCV000253263 benign Peutz-Jeghers syndrome 2018-01-03 criteria provided, single submitter clinical testing
Counsyl RCV000200266 SCV000487850 likely benign Peutz-Jeghers syndrome 2015-11-20 criteria provided, single submitter clinical testing
Color RCV000128297 SCV000537494 likely benign Hereditary cancer-predisposing syndrome 2015-08-10 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000213018 SCV000602236 likely benign not specified 2017-02-25 criteria provided, single submitter clinical testing
True Health Diagnostics RCV000128297 SCV000788219 likely benign Hereditary cancer-predisposing syndrome 2017-08-11 no assertion criteria provided clinical testing

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.