ClinVar Miner

Submissions for variant NM_000455.4(STK11):c.795G>A (p.Glu265=) (rs730881963)

Minimum review status: Collection method:
Minimum conflict level:
ClinVar version:
Total submissions: 6
Download table as spreadsheet
Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV000213019 SCV000211687 benign not specified 2014-07-11 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Ambry Genetics RCV000160977 SCV000212950 likely benign Hereditary cancer-predisposing syndrome 2014-07-17 criteria provided, single submitter clinical testing
Invitae RCV000204976 SCV000260114 likely benign Peutz-Jeghers syndrome 2017-12-26 criteria provided, single submitter clinical testing
Counsyl RCV000204976 SCV000488732 likely benign Peutz-Jeghers syndrome 2016-06-01 criteria provided, single submitter clinical testing
Color RCV000160977 SCV000686690 likely benign Hereditary cancer-predisposing syndrome 2016-03-06 criteria provided, single submitter clinical testing
PreventionGenetics,PreventionGenetics RCV000679324 SCV000806086 likely benign not provided 2017-10-24 criteria provided, single submitter clinical testing

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.