Submissions for variant NM_000455.5(STK11):c.734+17C>G

gnomAD frequency: 0.00006  dbSNP: rs751929304

Total submissions: 6

Submitter	RCV	SCV	Clinical significance	Condition	Last evaluated	Review status	Method	Comment
GeneDx	RCV000443296	SCV000515647	benign	not specified	2015-05-26	criteria provided, single submitter	clinical testing	This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Color Diagnostics, LLC DBA Color Health	RCV000580559	SCV000686680	likely benign	Hereditary cancer-predisposing syndrome	2016-05-29	criteria provided, single submitter	clinical testing
Genome-Nilou Lab	RCV001808801	SCV002057427	likely benign	Peutz-Jeghers syndrome	2021-07-15	criteria provided, single submitter	clinical testing
Labcorp Genetics (formerly Invitae), Labcorp	RCV001808801	SCV002384062	likely benign	Peutz-Jeghers syndrome	2024-01-25	criteria provided, single submitter	clinical testing
KCCC/NGS Laboratory, Kuwait Cancer Control Center	RCV001808801	SCV004015568	benign	Peutz-Jeghers syndrome	2023-07-07	criteria provided, single submitter	clinical testing
Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital	RCV000443296	SCV004242948	likely benign	not specified	2024-02-06	criteria provided, single submitter	clinical testing