Submissions for variant NM_000535.7(PMS2):c.1041G>A (p.Glu347=) (rs150515238)

Minimum review status:		Collection method:
Minimum conflict level:
		ClinVar version:

Total submissions: 5

Download table as spreadsheet

Submitter	RCV	SCV	Clinical significance	Condition	Last evaluated	Review status	Method	Comment
Ambry Genetics	RCV000215730	SCV000275897	likely benign	Hereditary cancer-predisposing syndrome	2015-05-14	criteria provided, single submitter	clinical testing
GeneDx	RCV000432282	SCV000523323	likely benign	not specified	2017-12-26	criteria provided, single submitter	clinical testing	This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Invitae	RCV000460855	SCV000562207	benign	Hereditary nonpolyposis colorectal neoplasms	2019-12-21	criteria provided, single submitter	clinical testing
Genetic Services Laboratory,University of Chicago	RCV000432282	SCV000596470	likely benign	not specified	2016-08-22	criteria provided, single submitter	clinical testing
Color	RCV000215730	SCV000686092	likely benign	Hereditary cancer-predisposing syndrome	2016-10-11	criteria provided, single submitter	clinical testing

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.