ClinVar Miner

Submissions for variant NM_000546.5(TP53):c.1082G>A (p.Gly361Glu) (rs587781663)

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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000129812 SCV000184626 uncertain significance Hereditary cancer-predisposing syndrome 2014-10-09 criteria provided, single submitter clinical testing Lines of evidence used in support of classification: Rarity in general population databases (dbsnp, esp, 1000 genomes),In silico models in agreement (benign)
Mayo Clinic Genetic Testing Laboratories,Mayo Clinic RCV000581885 SCV000692058 uncertain significance not specified no assertion criteria provided clinical testing

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