ClinVar Miner

Submissions for variant NM_000546.5(TP53):c.468C>T (p.Arg156=) (rs761222871)

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Total submissions: 5
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000162840 SCV000213327 likely benign Hereditary cancer-predisposing syndrome 2015-10-14 criteria provided, single submitter clinical testing Lines of evidence used in support of classification: Synonymous alterations with insufficient evidence to classify as benign
Color RCV000162840 SCV000906680 likely benign Hereditary cancer-predisposing syndrome 2018-01-05 criteria provided, single submitter clinical testing
Genetic Services Laboratory, University of Chicago RCV000502673 SCV000597514 likely benign not specified 2017-02-02 criteria provided, single submitter clinical testing
Invitae RCV000555591 SCV000629808 likely benign Li-Fraumeni syndrome 2017-11-21 criteria provided, single submitter clinical testing
PreventionGenetics RCV000679370 SCV000806239 likely benign not provided 2017-06-29 criteria provided, single submitter clinical testing

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