ClinVar Miner

Submissions for variant NM_000546.5(TP53):c.617T>C (p.Leu206Ser) (rs1555525804)

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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000507226 SCV000602275 uncertain significance not specified 2017-05-11 criteria provided, single submitter clinical testing
Ambry Genetics RCV000566251 SCV000664414 likely benign Hereditary cancer-predisposing syndrome 2016-07-22 criteria provided, single submitter clinical testing Lines of evidence used in support of classification: Other strong data supporting benign classification,In silico models in agreement (benign)

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