ClinVar Miner

Submissions for variant NM_000546.5(TP53):c.97-4A>T (rs746791390)

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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000563713 SCV000672377 uncertain significance Hereditary cancer-predisposing syndrome 2015-12-24 criteria provided, single submitter clinical testing Lines of evidence used in support of classification: Rarity in general population databases (dbsnp, esp, 1000 genomes),Insufficient or conflicting evidence
Color RCV000563713 SCV000691673 uncertain significance Hereditary cancer-predisposing syndrome 2018-09-09 criteria provided, single submitter clinical testing
Invitae RCV000229785 SCV000285217 likely benign Li-Fraumeni syndrome 2017-11-27 criteria provided, single submitter clinical testing

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