ClinVar Miner

Submissions for variant NM_000546.5(TP53):c.97-9C>T (rs202217267)

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Total submissions: 5
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Color RCV000580612 SCV000686786 likely benign Hereditary cancer-predisposing syndrome 2016-04-27 criteria provided, single submitter clinical testing
Counsyl RCV000410371 SCV000488528 uncertain significance Li-Fraumeni syndrome 1 2016-04-20 criteria provided, single submitter clinical testing
GeneDx RCV000161046 SCV000211776 benign not specified 2014-06-10 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Invitae RCV000195920 SCV000253318 likely benign Li-Fraumeni syndrome 2017-12-28 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000161046 SCV000602284 likely benign not specified 2017-05-27 criteria provided, single submitter clinical testing

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