ClinVar Miner

Submissions for variant NM_000546.6(TP53):c.189T>C (p.Ala63=)

dbSNP: rs2151042122
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Total submissions: 4
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Labcorp Genetics (formerly Invitae), Labcorp RCV001404410 SCV001606310 likely benign Li-Fraumeni syndrome 2024-08-20 criteria provided, single submitter clinical testing
Sema4, Sema4 RCV002256762 SCV002530430 likely benign Hereditary cancer-predisposing syndrome 2022-02-18 criteria provided, single submitter curation
Genome-Nilou Lab RCV002256762 SCV002582285 likely benign Hereditary cancer-predisposing syndrome 2022-06-18 criteria provided, single submitter clinical testing
Genome-Nilou Lab RCV002290708 SCV002582947 likely benign Li-Fraumeni syndrome 1 2022-06-18 criteria provided, single submitter clinical testing

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